Fasting Helps Avoid Collateral Damage in Fighting Bacterial Infections; Glucose Helps Avoid Collateral Damage in Fighting Viral Infections
The experiment flagged above about the effect of diet on fighting infection was only “performed on a single mouse strain (C57BL/6J) in one mouse facility,” but its results are striking. The three-minute video abstract is well done. (You can see it at the bottom of the image above.) The brief summary from that video is:
When the mice are not fed, or glucose is blocked, the mice with the bacterial infection live, while those with the viral infection live.
When the mice are fed glucose, the mice with the bacterial infection die, while those with the viral infection live.
If I understand the discussion section at the end of the paper, the issue is not effectiveness at killing the bacteria or viruses, but rather the damage to one’s own cells of the immune response. Ketones seemed to help protect cells from collateral damage when fighting bacteria, while glucose seemed to help protect cells from collateral damage when fighting viruses.
Note that collateral damage of this sort is only likely to be occurring in a big way if one is feeling symptoms. But if one is feeling symptoms of a viral infection, it might be OK to have some carbs, while if one is feeling symptoms of a bacterial infection, fasting might be helpful.
Again, this is one study in one laboratory using one strain of mice, but this shred of evidence might be useful given our current state of ignorance.
For annotated links to other posts on diet and health, see: